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● dr Justyna Mierziak-Derecka I have been associated with the Department of Genetic Biochemistry for several years. I started my adventure with this place from the analysis of hybrids resulting from the crossing of two transgenic lines, with overexpression of flavonoid synthesis genes and overexpression of the enzyme responsible for their stabilization, which was to obtain plants with an increased content of these compounds. I have also been involved in research that has shown that flavonoid-rich linseed straw extracts have cytotoxic properties against the MCF-7 human breast cancer cell line by increasing apoptosis. Then, as part of my doctoral dissertation and the implementation of the NCN Preludium project "Investigation of the function of beta-hydroxybutyrate in plant response to a fungal infection on the example of flax", I focused on beta-ketothiolase and one of the products of the reaction catalyzed by this enzyme, beta-hydroxybutyrate. Beta-hydroxybutyrate is known mainly as a component of the ketone bodies of animal cells, but little is known about its synthesis and function in plants. My research has shown that it is an important metabolite and regulatory molecule also in the plant world. During my doctoral studies, in addition to the research contained in the doctoral dissertation, I also participated in research on the way of benzenoid synthesis in flax and the composition and mutual relations of flax cell wall polymers. Currently, I am one of the contractors of the NCN OPUS project entitled "The impact of the non-pathogenic Fusarium oxysporum strain on the immune memory in flax", headed by Dr. Wioleta Wojtasik-Górna. The aim of this project is to determine the mechanisms responsible for the protective action of the non-pathogenic F. oxysporum strain against infection with a pathogenic strain.
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● Consultation hours: Monday, 12:00 - 14:00 |
